RESUMO
Vitamin D deficiency is common among women during pregnancy. This study aims to determine the prevalence of vitamin D deficiency and their shared modifiable environmental factors among pregnant women in Indonesia and Malaysia. METHODS: Blood samples of 844 third-trimester pregnant women (Indonesians: 311; Malaysians: 533) were collected to determine their serum 25(OH) D levels. Information on sun exposure and sun protection behaviours were obtained through face-to-face interviews. Dietary vitamin D intake was assessed by using a semiquantitative food frequency questionnaire. RESULTS: The prevalence of vitamin D deficiency (<30 nmol/L) among Indonesian and Malaysian pregnant women were 42.4% and 72.0%, respectively. Percentage of exposed body surface area was inversely associated with vitamin D deficiency among Indonesian pregnant women (OR = 0.21, 95% CI = 0.09-0.48). Among Malaysian pregnant women, higher intakes of dietary vitamin D were associated with lower risk of vitamin D deficiency (OR = 0.48, 95% CI = 0.29-0.81). Analysis of the combined cohorts revealed a lower risk of vitamin D deficiency among pregnant women who had a daily intake of at least 15 mcg vitamin D (OR = 0.58, 95% CI = 0.38-0.88) and exposure of more than 27% body surface area to the sunlight (OR = 0.30, 95% CI = 0.16-0.60). CONCLUSION: Despite abundant sunshine, vitamin D deficiency is prevalent among pregnant women in tropical countries. The present study suggests that nutrition education on vitamin D intake and sun exposure during pregnancy is necessary for primary prevention of vitamin D deficiency in pregnant women living in the tropical countries
Assuntos
Deficiência de Vitamina D , Superfície Corporal , Prevalência , Gestantes , Nutrição da Gestante , MalásiaRESUMO
Background: Contraception was the way to prevent pregnancy, both temporarily and permanently. Depot Medroxyprogesterone Acetate (DMPA) is a contraceptive injection of synthetic progesterone hormone and is injected every three months, which is most commonly used currently, but that emerging consequences of long time usage of contraception, especially the hormonal one, cannot be denied. This research was aimed to see difference in blood sugar, insulin and lipid profile in childbearing aged women who used DMPA injection and Non-Acceptors.Methods: The study was observational with the comparative cross sectional approach. Research was conducted in the Biomedical Laboratory in Andalas University and Regional Technical Service Unit (UPTD) Laboratory in West Sumatera Province. Data was taken from December 2017 until June 2018. The research sampled 48 DMPA acceptors and 48 non-Acceptors. Sampling technique used stratified random sampling. Examination of blood glucose was carried out by the enzymatic method of GOD-PAP, ELISA for insulin. Data were analyzed using independent T-test and if the data was not normal, non parametric Mann-Whitney test was used. The differences were considered statistically significant if the value of p<0.05.Results: The mean blood glucose acceptors 91.27mg/dl, non acceptors 88.83mg/dl and mean Insulin acceptors 23.63mIU/L, non akseptor 24.63mIU/L. The results showed that there were no significant differences between DMPA acceptors and non acceptors (p>0.05) in blood glucose (0.059) and insulin (p = 0.603).Conclusions: There were no significant differences in blood glucose and insulin levels between DMPA acceptors and non acceptors.
RESUMO
Background: A hormonal contraception which considered ideal is depot medroxy progesteron acetat. There are large number of acceptors choose this contraception because this contraception is considered safe, effective, and can be used after labor. The possible side effect which can occur are increase of lipid profile, body fat percentage, and waist circumference. The purpose of this study is to see the differences between lipid profile, body fat percentage, and the waist circumference of women of childbearing age who use depot medroxy progesteron acetat injection compared with non-acceptors.Methods: This study was observational study with a cross sectional comparative approach and was conducted at the Regional Technical Services Unit (UPTD) at Regional Health Laboratory in West Sumatera Province from December 2017 until June 2018. The samples were 46 DMPA acceptors and 46 non-acceptors. The sampling method used random sampling technique. The measurements of lipid profile was conducted with colorimetric enzymatic method, which is GPO-PAP for triglycerides, and CHOD-PAP for total cholesterol, HDL and LDL. The percentage of body fat examination was conducted using Bioelectrical Impedance Analysis (BIA). The obtained data were analyzed by using t-test. Abnormal data were confirmed by Mann-whitney non-parametric test with p<0.05.Results: The results showed a significant difference between DMPA acceptors and non-acceptors (p<0.05). In total cholesterol (p = 0.000), LDL (p = 0.000), triglycerides (p = 0.000), body fat percentage (p = 0.007), body mass index (p = 0.004), and waist circumference (p = 0.001). But, in HDL there was no significant difference between DMPA acceptors and non-acceptors with p value = 0.302 (p>0.05). There were significant differences in total cholesterol, LDL, triglycerides, fat percentage, body mass index, and the circumference of waist in both DMPA acceptors and non acceptors. There were no significant difference in HDL levels between DMPA acceptors and non acceptors.Conclusions: There were significant differences in total cholesterol, LDL, triglycerides, fat percentage, body mass index, and waist circumference between DMPA acceptors and non-acceptors. There was no significant difference in HDL between DMPA acceptors and non-acceptors.
RESUMO
Background and Aims: Preoperative fasting and surgery cause uncomfortable condition, metabolic stress and insulin resistance for the patient. A recent study in colorectal patients indicates that even small elevations of insulin resistance increase the risk of complications. Preoperative carbohydrate can reduce perioperative discomfort and insulin resistance. We investigated the effects of honey as preoperative carbohydrate-rich drink on the residual gastric contents, perioperative discomfort, and insulin resistance. Methods: Randomized, prospective, controlled study. Thirty colorectal cancer patients who underwent elective open colorectal surgery were randomized and divided into the treatment or control group. Patients in treatment group (n = 15) received 250 ml water containing 50 ml honey on the evening and 2-3 hours preoperatively. Control patients (n = 15) underwent overnight fasting. Three different discomfort variables (thirst, hunger and tiredness), residual gastric content, plasma glucose, insulin concentrations and insulin resistance index were recorded during the perioperative period. Results: Patient and operative characteristics did not differ between groups. There was no statistical difference between the two groups with respect to gastric residue content. Subjective well-being was significantly better in the treatment group. Plasma glucose, serum insulin levels and insulin resistance index were found to remain significantly lower in the treatment group. Conclusion: The preoperative honey drink does not appear to alter the volume of residual gastric contents, suggesting that this is safe procedure. Preoperative honey intake is advantageous due to reducing perioperative discomfort and insulin resistance.